When it comes to bedbug bites, everyone reacts differently. Some people just have small red marks, while others have a more severe allergic reaction to the bedbug bites. The best treatment options for bedbug bites include anti-itch cream, topical antiseptics (to ward off infection), and oral antihistamines. These treatments for bedbug bites are over-the-counter. If you have a severe reaction to bedbug bites, see a doctor; you may need a corticosteroid. See Also: Is This a Bed Bite?; Are Bedbug Bites Dangerous?; and Pictures of BedBug Bites
lou_bugs_pix/Flickr/CC BY-ND 2.0
For mild bedbug bites, an antibiotic cream is recommended. I like Neosporin + Plus Pain Relief. This maximum strength first aid antibiotic cream is available over the counter in a variety of sizes, and can be taken along while traveling.
I like the Neosporin spray for small children that don't want to have a cream rubbed on them, or are sensitive to you touching their "boo-boos." It's also extremely convenient to carry, as you can throw it in a purse or a pocket, even add it to a keyring.
Hibiclens is a respected product often used in hospitals. Use this antiseptic skin cleanser to wash your bedbug bites in the shower every day.
These wipes work best for small areas. Wipe them right on the bedbug bites to guard against infection. I like the no-sting variety best.
Many swear by this tried-and-true remedy, an antiseptic powder that heals and fights infection. It's a good all-around addition to your medicine cabinet, with or without bedbug bites.
It's always a good idea to keep a tube of this handy. You can rub it right on the bedbug bites and it will stop the itch almost immediately. Perfect when you just can't stop yourself from scratching (or need to get some sleep).
There are a number of good antihistamine tablets on the market, including Benadryl Ultratabs and Tylenol Severe Allergy Antihistamine. This type of product is recommended if you have an allergic reaction to the bedbug bites. Be cautious, as these can make you very drowsy.